• 
  Belgrano – Huracan

  4 September

• 
  Atletico Platense – Deportivo

  4 September

• 
  Rio Cuarto – Sarmiento

  4 September

• 
  Deportes Concepcion – Audax

  5 September

• 
  Deportivo Pereira – Ind

  4 September

• 
  America de Cali – Alianza

  3 September

• 
  Nottingham – Tottenham

  5 September

• 
  Brighton – Leeds Utd

  5 September

• 
  Manchester City – Coventry

  5 September

• 
  Fulham – Crystal Palace

  5 September

• 
  Brentford – Sunderland

  5 September

• 
  Newcastle – Bournemouth

  5 September

• 
  Ipswich Town – Liverpool

  4 September

• 
  PSG – AS Monaco

  4 September

• 
  Lyon – Auxerre

  4 September

• 
  Toulouse – Lille

  3 September

• 
  Borussia M – Elversberg

  5 September

• 
  Leverkusen – Union

  5 September

• 
  Werder Bremen – RB

  5 September

• 
  Paderborn – Freiburg

  5 September

• 
  Hoffenheim – Dortmund

  5 September

• 
  Stuttgart – Cologne

  4 September

• 
  Fiorentina – Torino

  5 September

• 
  Genoa – Como

  4 September

• 
  Spartak M – Torpedo NN

  5 September

• 
  Severstal – Salavat

  5 September

• 
  Avtomobilist – Dynamo

  5 September

• 
  Lokomotiv – Traktor

  5 September

• 
  Juarez – Pachuca

  5 September

• 
  Estrela – Famalicao

  5 September

• 
  Porto – Moreirense

  4 September

• 
  CFR Cluj – Farul

  4 September

• 
  Zenit – CSKA

  5 September

• 
  Krylia – Krasnodar

  5 September

• 
  Athletic Bilbao – Atletico

  5 September

• 
  Real Betis – Real

  4 September

• 
  Real Sociedad – Celta

  3 September

• 
  Basaksehir – Galatasaray

  4 September

• 
  Kryvbas – Kolos

  5 September

• 
  Kharkiv – Obolon

  5 September

• 
  Polissya – Kudrivka

  4 September

• 
  Chornomorets – Livyi

  4 September

• 
  New – Nashville

  5 September

• 
  Asta – Zaqatala

  4 September

• 
  Simal – Cabrayil

  4 September

• 
  Kapaz – Shamakhi

  4 September

• 
  Gabala – Imisli

  4 September

• 
  Volna Pinsk – Dinamo

  4 September

• 
  Molodechno – BATE Res

  4 September

• 
  Minsk Res – Niva

  4 September