• 
  Union – Instituto

  8 September

• 
  Barracas Central – Argentinos

  7 September

• 
  Vitoria-BA – Gremio-RS

  8 September

• 
  Barcelona – Feyenoord

  9 September

• 
  Real Madrid – Inter

  8 September

• 
  Lille – Real Betis

  8 September

• 
  Dortmund – Villarreal

  8 September

• 
  Porto – Manchester City

  8 September

• 
  AEK – LASK

  8 September

• 
  Brügge – Aston Villa

  8 September

• 
  Deportes – Cobresal

  8 September

• 
  Orense – Guayaquil City

  8 September

• 
  Mushuc Runa – Leones

  8 September

• 
  Emelec – Manta

  8 September

• 
  Barys – Salawat Julajew

  9 September

• 
  Lokomotive – Kunlun RS

  8 September

• 
  Neftechimik – Sotschi

  8 September

• 
  Metallurg Mg – Amur

  8 September

• 
  Llaneros – Deportes

  8 September

• 
  Utrecht – Go

  8 September

• 
  Estoril Praia – Arouca

  7 September

• 
  Elche – Real Sociedad

  7 September

• 
  Sahdag – Karvan

  9 September

• 
  Fluminense – Atletico

  8 September

• 
  Boca Juniors – Sao Paolo

  9 September

• 
  Santa Fe – Vasco de Gama

  8 September

• 
  Bolton Wanderers – West

  8 September

• 
  Watford – Preston

  8 September

• 
  Wrexham – Burnley

  8 September

• 
  Southampton – Swansea

  8 September

• 
  Blackburn – Sheffield

  8 September

• 
  Cardiff City – Stoke

  8 September

• 
  Exeter City – Tottenham

  8 September

• 
  Millwall – Newcastle

  8 September

• 
  Crystal – Middlesbrough

  8 September

• 
  Bournemouth – Lincoln

  8 September

• 
  Sunderland – Hull City

  8 September

• 
  Leyton Orient – Bradford

  8 September

• 
  Nomme Kalju – Nomme

  8 September

• 
  Trans Narva – Flora

  8 September

• 
  Atletico Nacional – Deportivo

  8 September

• 
  LA Dodgers – Cincinnati

  9 September

• 
  San – Saint-Louis

  9 September

• 
  Seattle – Texas

  9 September

• 
  San Diego – Washington

  9 September

• 
  Oakland – Toronto

  9 September

• 
  Chi – Pittsburgh

  9 September

• 
  Milwaukee – Chi Cubs

  9 September

• 
  Kansas City – Arizona

  9 September

• 
  Atlanta – Tampa Bay

  9 September