• 
  Union – Instituto

  8 September

• 
  Barracas Central – Argentinos

  7 September

• 
  Racing – Atletico

  7 September

• 
  River Plate – Independiente

  6 September

• 
  Lanus – Defensa

  6 September

• 
  Central – Independiente

  6 September

• 
  Rosario Central – Newell`s

  6 September

• 
  Vitoria-BA – Gremio-RS

  8 September

• 
  Corinthians – Chapecoense

  6 September

• 
  Botafogo-RJ – Palmeiras

  6 September

• 
  Cruzeiro-MG – Athletico-PR

  6 September

• 
  Remo – Flamengo-RJ

  6 September

• 
  Inter-RS – Santos-SP

  6 September

• 
  Coritiba – Mirassol

  6 September

• 
  Deportes – Cobresal

  8 September

• 
  Palestino – Univ

  6 September

• 
  Huachipato – Colo Colo

  6 September

• 
  O`Higgins – Union

  6 September

• 
  La Serena – Nublense

  6 September

• 
  Eintracht – Augsburg

  6 September

• 
  Hamburg – Mainz 05

  6 September

• 
  Orense – Guayaquil City

  8 September

• 
  Mushuc Runa – Leones

  8 September

• 
  Emelec – Manta

  8 September

• 
  Aucas – Barcelona SC

  7 September

• 
  CD Cuenca – Libertad

  7 September

• 
  Delfin – Univ

  6 September

• 
  Arsenal – Chelsea

  6 September

• 
  Marseille – Paris

  6 September

• 
  Angers – Rennes

  6 September

• 
  Asteras – Iraklis

  7 September

• 
  Udinese – Lazio

  7 September

• 
  Cagliari – Lecce

  7 September

• 
  Juventus – Mailand

  6 September

• 
  Bologna – Sassuolo

  6 September

• 
  Ak Bars – Admiral

  7 September

• 
  ZSKA – Spartak M

  7 September

• 
  SKA – Dynamo M

  7 September

• 
  Dinamo Mn – Torpedo NN

  7 September

• 
  Sewerstal – Lada Tl

  7 September

• 
  Barys – Sibir

  7 September

• 
  Awtomobilist – Traktor

  7 September

• 
  Avangard – Salawat

  7 September

• 
  Neftechimik – Kunlun RS

  6 September

• 
  Llaneros – Deportes

  8 September

• 
  Deportivo – Millonarios

  7 September

• 
  Inter de Bogota – Aguilas

  6 September

• 
  Cruz Azul – Santos

  7 September

• 
  Den Haag – Fortuna

  6 September

• 
  Estoril Praia – Arouca

  7 September