• 
  Deportes – Nublense

  3 September

• 
  Deportivo Pereira – Ind

  4 September

• 
  America de Cali – Alianza

  3 September

• 
  Santa Fe – Millonarios

  3 September

• 
  Ipswich Town – Liverpool

  4 September

• 
  PSG – AS Monaco

  4 September

• 
  Lyon – Auxerre

  4 September

• 
  Toulouse – Lille

  3 September

• 
  Stuttgart – Cologne

  4 September

• 
  Genoa – Como

  4 September

• 
  Real Betis – Real

  4 September

• 
  Real Sociedad – Celta

  3 September

• 
  Polissya – Kudrivka

  4 September

• 
  Chornomorets – Livyi

  4 September

• 
  Asta – Zaqatala

  4 September

• 
  Simal – Cabrayil

  4 September

• 
  MOIK – Sahdag

  3 September

• 
  Baku Sporting – Karvan

  3 September

• 
  Kapaz – Shamakhi

  4 September

• 
  Gabala – Imisli

  4 September

• 
  Volna Pinsk – Dinamo

  4 September

• 
  Molodechno – BATE Res

  4 September

• 
  Minsk Res – Niva

  4 September

• 
  Isloch – BATE

  3 September

• 
  Gremio-RS – Inter-RS

  4 September

• 
  Vitoria-BA – Vasco

  3 September

• 
  Santos-SP – Palmeiras

  3 September

• 
  Septemvri – Botev Vratsa

  4 September

• 
  Vancouver – Montreal

  3 September

• 
  Salzburg – Koelner Haie

  3 September

• 
  Graz – Fribourg

  3 September

• 
  Dynamo Pardubice – Tychy

  3 September

• 
  Tappara – Bili

  3 September

• 
  Plzen – Rogle

  3 September

• 
  Internacional Palmira – Real

  4 September

• 
  Cavalier – Portmore

  4 September

• 
  Salcedo – Mount Pleasant

  3 September

• 
  Bradford Bulls – Castleford

  3 September

• 
  Gyori ETO – Ferencvaros

  3 September

• 
  Cagliari – Hellas Verona

  3 September

• 
  Palermo – Mantova

  3 September

• 
  Al-Baqa`a – Doqarah

  3 September

• 
  Tobol 2 – Kairat-Zhastar

  3 September

• 
  Astana-2 – Taraz

  3 September

• 
  Shakhter – Khan-Tengri

  3 September

• 
  Arys – Batyr

  3 September

• 
  Akademiya Ontustik – Aktobe

  3 September

• 
  America – Monterrey

  3 September

• 
  Toluca – Leon

  3 September

• 
  Banga – Panevezys

  3 September