• 
  Inter de Bogota – Deportivo

  28 August

• 
  Once Caldas – Deportes

  28 August

• 
  Atletico Nacional – Deportivo

  27 August

• 
  America de Cali – Atletico

  27 August

• 
  Crystal Palace – Manchester

  28 August

• 
  Bayern – Stuttgart

  28 August

• 
  Milan – Venezia

  28 August

• 
  Akron – CSKA

  28 August

• 
  Racing – Elche

  28 August

• 
  Barcelona – Athletic

  27 August

• 
  Celta – Osasuna

  27 August

• 
  Kolos – Obolon

  28 August

• 
  Atletico – Instituto

  28 August

• 
  Estudiantes LP – Barracas

  27 August

• 
  Aldosivi – Independiente

  26 August

• 
  Inter-RS – Gremio-RS

  28 August

• 
  Vasco – Vitoria-BA

  27 August

• 
  Palmeiras – Santos-SP

  27 August

• 
  Colo Colo – Union

  27 August

• 
  Olimpia – Deportivo

  28 August

• 
  Mixco – Alianza

  28 August

• 
  Alajuelense – Plaza

  27 August

• 
  Xelaju MC – LA Firpo

  27 August

• 
  Marathon – Real Esteli

  27 August

• 
  Herediano – Antigua GFC

  27 August

• 
  River Plate – Santa Fe

  27 August

• 
  Fulham – Bournemouth

  27 August

• 
  Chelsea – Luton Town

  27 August

• 
  Wigan Warriors – Hull

  27 August

• 
  Larne – Lincoln Red Imps

  27 August

• 
  Hibernian – Gent

  27 August

• 
  Partizan – Getafe

  27 August

• 
  Rijeka – Midtjylland

  27 August

• 
  Brighton – Tromsoe

  27 August

• 
  Austria Vienna – Braga

  27 August

• 
  Ajax – Sion

  27 August

• 
  Hapoel – Atalanta

  27 August

• 
  St – Nordsjaelland

  27 August

• 
  Pafos – Dinamo City

  27 August

• 
  Inter – Drita

  27 August

• 
  Brann – PAOK

  27 August

• 
  Copenhagen – Inter Turku

  27 August

• 
  Rakow – Hajduk

  27 August

• 
  Freiburg – Motherwell

  27 August

• 
  AS Monaco – Gornik

  27 August

• 
  Qarabag – Twente

  27 August

• 
  Maccabi – Lugano

  27 August

• 
  Jablonec – Rangers

  27 August

• 
  Ferencvaros – Trabzonspor

  27 August

• 
  Thun – Lech Poznan

  27 August